I’m not convinced that new label vigilantly reflects the fresh belongings in brand new papers

Authors’ impulse

What’s the opportinity for determining prompt-growing and you will sluggish-growing necessary protein-coding genetics? In the event the experience merely “Fool around with Ka”, I might believe folks have over one to just before.

Authors’ impulse

We have changed this new title so you can “Nonsynonymous replacing price (Ka) was a fairly consistent factor for determining prompt-changing and slow-changing proteins-coding genes”. You will find searched the fresh new relevant literature cautiously and also perhaps not found books which have complete eg thorough recommendations towards methods.

Recommendations

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Demuth JP, De- Bie T, Stajich JE, Cristianini Letter, Hahn MW: The newest progression out of mammalian gene parents. PLoS That. 2006, 1: e85-/log.pone.0000085.

Williamson SH, Hubisz MJ, Clark AG, Payseur BA, Bustamante Computer game, Nielsen R: Localizing recent adaptive development throughout the person genome. PLoS Genet. 2007, 3: e90-/log.pgen.0030090.

Bustamante Video game, Fledel-Alon A good, Williamson S, Nielsen Roentgen, Hubisz MT, Glanowski S, Tanenbaum DM, Light TJ, Sninsky JJ, Hernandez RD, Civello D, Adams MD, Cargill Meters, Clark AG: Pure alternatives into healthy protein-programming genetics regarding the person genome. Character. 2005, 437: 1153-1157. /nature04240.

Nielsen R, Bustamante C, Clark AG, Glanowski S, Sackton TB, Hubisz MJ, Fledel-Alon A good, Tanenbaum DM, Civello D, Light TJ, J Sninsky J, Adams MD, Cargill Meters: A browse having seriously chosen genes regarding the genomes out of humans and you can chimpanzees. PLoS Biol. 2005, 3: e170-/diary.pbio.0030170.

Kosiol C, Vinar T, weil Fonseca RR, Hubisz MJ, Bustamante Computer game, Nielsen R, Siepel A great: Designs out of confident selection in the six Mammalian genomes. PLoS Genet. 2008, 4: e1000144-/diary.pgen.1000144.

Clark AG, Glanowski S, Nielsen R, Thomas PD, Kejariwal An excellent, Todd MA, Tanenbaum DM, Civello D, Lu F, Murphy B, Ferriera S, Wang Grams, Zheng X, Light TJ, Sninsky JJ, Adams MD, Cargill Meters: Inferring nonneutral progression of individual-chimp-mouse orthologous gene trios. Technology. 2003, 302: 1960-1963. /research.1088821.

Locke DP, Hillier LW, Warren Rest room, Worley KC, Nazareth LV, Muzny DM, Yang SP, Wang Z, Chinwalla At the, Minx P, et al: Comparative and you may group research regarding orang-utan genomes. Nature. 2011, 469: 529-533. /nature09687.

Gibbs RA, Rogers J, Katze Mg, Bumgarner Roentgen, Weinstock GM, Mardis Emergency room, Remington KA, Strausberg RL, Venter JC, Wilson RK, et al: Evolutionary and you can biomedical skills regarding rhesus macaque genome. Science. 2007, 316: 222-234. /science.1139247.

Wade CM, Giulotto E, Sigurdsson S, Zoli Meters, Gnerre S, Imsland F, Lear TL, Adelson DL, Bailey E, Bellone RR, mais aussi al: Genome series, relative study, and you will population genes of home-based pony. Technology. 2009, 326: 865-867. /technology.1178158.

Lindblad-Toh K, Go CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal Meters, Fasten Meters, Chang JL, Kulbokas EJ, Zody MC, ainsi que al: Genome succession, comparative investigation and you may haplotype structure of the residential dog. Character. 2005, 438: 803-819. /nature04338.

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